SPENGA member offer · $50 off with code SPENGA50
SPENGA Powered by Apex Meds Get started
Skin · Injectable

Glow Stack

BPC-157 + TB-500 + GHK-Cu

Two repair peptides, plus the one your skin already knows.

BPC-157 and TB-500 with GHK-Cu, the copper peptide, in a single physician-prescribed protocol. Evaluated by a licensed Apex MD provider and filled by a licensed U.S. pharmacy.

$249per month · injectable

SPENGA members: $50 off with code SPENGA50

  • Physician prescribed
  • Licensed U.S. pharmacy
  • Ongoing medical support
  • Arrives reconstituted
Apex Meds Glow Stack vial in SPENGA green
Form
Subcutaneous injection
Course
A set cycle, then a break
Prescribed by
Licensed Apex MD provider
Contains
BPC-157, TB-500, GHK-Cu
What it is

Glow Stack, in plain terms

Glow is the common name for a blend of three peptides: BPC-157, TB-500 and GHK-Cu. It is a marketplace name, not a drug name.

GHK-Cu is a three-amino-acid peptide bound to copper. It occurs naturally in human plasma, where it was identified in 1973, and published reviews report that levels fall from about 200 ng/mL at age 20 to about 80 ng/mL by age 60.

How it works

What it does in the body

Each peptide is proposed to act on a different part of tissue repair. GHK-Cu is associated with collagen and the remodelling of the skin's support matrix. BPC-157 supports new blood vessel growth in animal models. Thymosin beta-4 helps cells migrate to where they are needed.

All of that comes from work on the individual peptides, most of it in the laboratory or in animals. None of it has been shown for the blend in people.

The evidence

What the research shows, and what it doesn’t

Every finding is labelled by the kind of study it came from, with the source linked.

Human trial ยท topical

Applied to the face twice daily for eight weeks, GHK-Cu reduced wrinkle volume by 55.8% and depth by 32.8% relative to a control serum. This was a cream, not an injection.

Badenhorst et al., J Aging Science, 2016
Animal and lab

GHK-Cu prompted skin cells to make more collagen, elastin and glycosaminoglycans in the lab, and sped wound healing in animal models.

Pickart & Margolina, Int J Mol Sci, 2018
Animal and lab

Of 36 studies of BPC-157 in a 2025 systematic review, 35 were animal or lab studies. They showed improved healing of muscle, tendon and ligament.

Vasireddi et al., systematic review, 2025
Not yet studied

No published study, in people or animals, has tested these three peptides together, and the human evidence for GHK-Cu is for topical use only.

FDA, bulk drug substances safety review

Published research describes what was observed in a study. It is not a promise of what any product will do for you. Your provider will talk through what is realistic.

What to expect

On the protocol

01

How it's taken

Small injections just under the skin over a set cycle, followed by a break. Your provider sets the dose, the schedule and the length of the cycle. It arrives already reconstituted by the pharmacy, so there is no powder to mix and nothing to measure out.

02

What people report

Patients describe recovery changes first and skin changes over the following weeks. These are patient reports, not trial outcomes, and results vary.

03

Three at once

Starting three peptides together means a benefit or a side effect cannot be pinned to any one of them. Your provider may suggest starting with a single peptide.

Safety

Know this before you start

Your provider reviews your full history. Tell them about every medication and condition, including any history of cancer.

Reported side effects

  • Redness, itching, swelling or bruising at the injection site
  • Headache or lightheadedness
  • Nausea or fatigue
  • Long-term safety has not been studied

Who should not use it

  • Active cancer or any history of cancer without oncologist clearance
  • Pregnancy or breastfeeding
  • Wilson's disease or another copper metabolism disorder
  • Liver impairment
  • Athletes subject to drug testing
Tested athletes

Not for drug-tested athletes

BPC-157 and TB-500 are both prohibited at all times under World Anti-Doping Agency rules, so tested athletes cannot use this blend.

FAQ

Glow Stack questions, answered

What is in the Glow Stack?

Three peptides in one protocol: BPC-157, TB-500 and GHK-Cu, the copper peptide.

Has the blend been studied in people?

No. There are no human trials of the combination. Evidence for the individual peptides comes mostly from animal and lab studies, and the human skin studies of GHK-Cu used a cream.

How is it different from the GHK-Cu cream?

The cream is applied to the skin and is the form the human skin studies used. The Glow Stack is an injectable blend that also contains two repair peptides. Your provider can help you decide which fits your goal.

Is it FDA-approved?

No. None of the three ingredients is FDA-approved. When prescribed it is a compounded medication, which has not been reviewed by the FDA for safety, effectiveness or quality.

Who should not use it?

Anyone with active or recent cancer, anyone pregnant or breastfeeding, and anyone with Wilson's disease or another copper metabolism disorder.

Can I use it if I compete in a tested sport?

No. BPC-157 and TB-500 are banned at all times under WADA rules.

Keep looking

Other peptides for SPENGA members

Exclusive SPENGA member access

Start with Glow Stack

Answer a few questions. A licensed Apex MD provider decides whether it is right for you.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Prescription products require an online evaluation with a licensed medical professional, who will determine whether a prescription is appropriate. Compounded medications are not FDA-approved and have not been evaluated by the FDA for safety, effectiveness or quality. Research cited on this site describes published studies and is not a claim about what any product will do for you. Individual results vary.

Sources
  1. Badenhorst et al., J Aging Science, 2016. https://www.walshmedicalmedia.com/open-access/effects-of-ghkcu-on-mmp-and-timp-expression-collagen-and-elastin-production-and-facial-wrinkle-parameters-2329-8847-1000166.pdf
  2. Pickart & Margolina, Int J Mol Sci, 2018. https://pmc.ncbi.nlm.nih.gov/articles/PMC6073405/
  3. Vasireddi et al., systematic review, 2025. https://pmc.ncbi.nlm.nih.gov/articles/PMC12313605/
  4. FDA, bulk drug substances safety review. https://www.fda.gov/drugs/human-drug-compounding/certain-bulk-drug-substances-use-compounding-may-present-significant-safety-risks